Polio history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Clinical manifestations of poliovirus infection range from asymptomatic (most infections) to symptomatic, including acute flaccid paralysis of a single limb to quadriplegia, respiratory failure, and rarely, death.
History and Symptoms
About 95% of patients with an healthy immune system do not develop symptom of poliomyelitis. Approximately 4 to 8% of infections with poliovirus result in minor, nonspecific disease, without clinical or laboratory evidence of CNS involvement. This form of the disease is called abortive poliomyelitis.
Abortive Poliomyelitis
Commons symptoms of abortive poliomyelitis may mimic those of gastroenteritis, acute respiratory infection, and influenza-like disease, such as:[1]
Non-Paralytic Poliomyelitis
Common symptoms of non-paralytic poliomyelitis may include:[2]
Paralytic Poliomyelitis
Common symptoms of paralytic poliomyelitis may include those of non-paralytic poliomyelitis. Additional symptoms may include:[3][4][5]
- Muscle weakness
- Asymmetrical paralysis
- Muscle atrophy
- Tremors
- Skeletal deformities
References
- ↑ Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
- ↑ Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
- ↑ Wood, Lawrence D. H.; Hall, Jesse B.; Schmidt, Gregory D. (2005). Principles of Critical Care, Third Edition. McGraw-Hill Professional. p. 870. ISBN 0-07-141640-4.
- ↑ Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
- ↑ Alcalá H (1993). "[The differential diagnosis of poliomyelitis and other acute flaccid paralyses]". Bol Med Hosp Infant Mex. 50 (2): 136–44. PMID 8442872.