Aortic stenosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Mohammed A. Sbeih, M.D. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]
Overview
The most common risk factor for the development of aortic stenosis is the presence of a congenital bicuspid aortic valve. Risk factors that may speed up the progression of aortic stenosis include the same risk factors as atherosclerosis.
Risk Factors
- Common risk factors for the development of aortic stenosis include:
- Acute rheumatic fever (< 10% of cases)
- Age-related progressive calcification of the normal tricuspid aortic valve ( >50% of cases)
- Congenital bicuspid aortic valve that may subsequently become calcified later in life (30-40% of cases)
- Other risk factors that may speed up the progression of aortic stenosis include the same risk factors as atherosclerosis:
Other risk factors of aortic stenosis include:
- Radiation therapy or treatment of cancer, such as breast cancer or lymphoma[1]
- High lipoprotein a
- Renal failure
- Disorders of calcium metabolism
References
- ↑ Hull MC, Morris CG, Pepine CJ, Mendenhall NP (2003). "Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of hodgkin lymphoma treated with radiation therapy". JAMA. 290 (21): 2831–7. doi:10.1001/jama.290.21.2831. PMID 14657067.