Peripheral arterial disease causes
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Peripheral arterial disease Microchapters |
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Differentiating Peripheral arterial disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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AHA/ACC Guidelines on Management of Lower Extremity PAD |
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Guidelines for Structured Exercise Therapy for Lower Extremity PAD |
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Guidelines for Minimizing Tissue Loss in Lower Extremity PAD |
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Guidelines for Revascularization of Claudication in Lower Extremity PAD |
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Guidelines for Management of Acute Limb Ischemial in Lower Extremity PAD |
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Guidelines for Longitudinal Follow-up for Lower Extremity PAD |
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Peripheral arterial disease causes On the Web |
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American Roentgen Ray Society Images of Peripheral arterial disease causes |
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Directions to Hospitals Treating Peripheral arterial disease |
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Risk calculators and risk factors for Peripheral arterial disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby
Overview
Peripheral arterial disease (PAD) is most commonly a manifestation of atherosclerosis resulting from vascular inflammation. Other uncommon causes should be suspected when the PAD occurs at a young age and in the context of a positive history. Uncommon causes include degenerative diseases (Marfan's syndrome and Ehlers-Danlos syndrome), dysplastic disorders (fibromuscular dysplasia), inflammatory diseases (arteritis) and hypercoagulable states.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
Causes by Organ System
| Cardiovascular | Arteriomegaly, arteritis, atherosclerosis, Erdheim cystic medial necrosis, fibromuscular dysplasia, hypertension, Leriche's syndrome, multifocal fibrosclerosis, Sneddon syndrome, Takayasu's arteritis, temporal arteritis, thromboangiitis obliterans, thromboembolism |
| Chemical / poisoning | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | Deafness peripheral neuropathy and arterial disease, Ehlers-Danlos syndrome, heterozygous familial hypercholesterolemia, Marfan's syndrome, pseudoxanthoma elasticum, forme fruste |
| Hematologic | Homocysteinemia, Hypercoagulable state, In situ thrombosis, Thrombophilias |
| Iatrogenic | Surgery, In situ thrombosis |
| Infectious Disease | No underlying causes |
| Musculoskeletal / Ortho | No underlying causes |
| Neurologic | Neurofibromatosis, Sneddon syndrome |
| Nutritional / Metabolic | Hyperlipidemia, lipoproteinemia |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | Cancer |
| Opthalmologic | Sneddon syndrome |
| Overdose / Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal / Electrolyte | No underlying causes |
| Rheum / Immune / Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Dental | No underlying causes |
| Miscellaneous | Obesity, old age, prolonged immobilization, sedentary life style, smoking |
Causes in Alphabetical Order
- Arteriomegaly
- Arteritis
- Atherosclerosis
- Cancer
- Deafness peripheral neuropathy and arterial disease
- Diabetes
- Ehlers-Danlos syndrome
- Erdheim cystic medial necrosis
- Fibromuscular dysplasia
- Heterozygous familial hypercholesterolemia
- Homocysteinemia
- Hypercoagulable state
- Hyperlipidemia
- Hypertension
- In situ thrombosis
- Leriche's syndrome
- Lipoproteinemia
- Marfan's syndrome
- Multifocal fibrosclerosis
- Neurofibromatosis
- Obesity
- Old age
- Prolonged immobilization
- Pseudoxanthoma elasticum, forme fruste
- Sedentary life style
- Smoking
- Sneddon syndrome
- Surgery
- Takayasu's arteritis
- Temporal arteritis
- Thromboangiitis obliterans
- Thromboembolism
- Thrombophilias
- Vasculitis