Peripheral arterial disease causes
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Peripheral arterial disease Microchapters |
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Differentiating Peripheral arterial disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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AHA/ACC Guidelines on Management of Lower Extremity PAD |
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Guidelines for Structured Exercise Therapy for Lower Extremity PAD |
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Guidelines for Minimizing Tissue Loss in Lower Extremity PAD |
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Guidelines for Revascularization of Claudication in Lower Extremity PAD |
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Guidelines for Management of Acute Limb Ischemial in Lower Extremity PAD |
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Guidelines for Longitudinal Follow-up for Lower Extremity PAD |
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Peripheral arterial disease causes On the Web |
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American Roentgen Ray Society Images of Peripheral arterial disease causes |
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Directions to Hospitals Treating Peripheral arterial disease |
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Risk calculators and risk factors for Peripheral arterial disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby
Overview
Peripheral arterial disease (PAD) is most commonly a manifestation of atherosclerosis resulting from vascular inflammation. Other uncommon causes should be suspected when the PAD occurs at a young age and in the context of a positive history. Uncommon causes include degenerative diseases (Marfan's syndrome and Ehlers-Danlos syndrome), dysplastic disorders (fibromuscular dysplasia), inflammatory diseases (arteritis) and hypercoagulable states.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Arterial dissection
- Atheroembolism
- Atherosclerosis
- Thromboangiitis obliterans
- Thromboembolism
- Thrombosed aneurysm
Causes by Organ System
| Cardiovascular | Arterial dissection, arteriomegaly, arteritis, atheroembolism, atherosclerosis, Buergers disease, Erdheim cystic medial necrosis, fibromuscular dysplasia, hypertension, Leriche's syndrome, multifocal fibrosclerosis, Sneddon syndrome, Takayasu's arteritis, temporal arteritis, thromboangiitis obliterans, thromboembolism, thrombosed aneurysm, vasculitis |
| Chemical / poisoning | No underlying causes |
| Dermatologic | Vasculitis |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | Deafness peripheral neuropathy and arterial disease, Ehlers-Danlos syndrome, heterozygous familial hypercholesterolemia, Marfan's syndrome, pseudoxanthoma elasticum |
| Hematologic | Homocysteinemia, Hypercoagulable state, thrombophilia, thrombosis |
| Iatrogenic | Radiation fibrosis, surgery, thrombosis |
| Infectious Disease | No underlying causes |
| Musculoskeletal / Ortho | No underlying causes |
| Neurologic | Neurofibromatosis, Sneddon syndrome |
| Nutritional / Metabolic | Hyperlipidemia, lipoproteinemia |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | Cancer, tumor |
| Opthalmologic | Sneddon syndrome |
| Overdose / Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal / Electrolyte | No underlying causes |
| Rheum / Immune / Allergy | Buergers disease, retroperitoneal fibrosis, thromboangiitis obliterans, vasculitis |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | Retroperitoneal fibrosis |
| Dental | No underlying causes |
| Miscellaneous | Obesity |