Hemophilia classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Haemophilia may be classified into three subtypes:Haemophilia A , Haemophilia B, Haemophilia C.

Classification

• Haemophilia A is a recessive X-linked genetic disorder involving a lack of functional clotting Factor VIII and represents 80% of haemophilia cases.
• Haemophilia B is a recessive X-linked genetic disorder involving a lack of functional clotting Factor IX. It comprises approximately 20% of haemophilia cases.
• Haemophilia C is an autosomal genetic disorder (i.e. not X-linked) involving a lack of functional clotting Factor XI. Haemophilia C is not completely recessive, as heterozygous individuals also show increased bleeding