Brain Stem Gliomas MRI

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Differentiating Brain Stem Gliomas from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

MRI

MRI is the imaging modality of choice for brainstem gliomas. The findings will vary with the tumor type.[1]

  • Diffuse brainstem gliomas

The pons is enlarged, with the basilar artery displaced anteriorly against the clivus and potentially engulfed. The floor of the fourth ventricle is flattened ("flat floor of fourth ventricle sign") and obstructive hydrocephalus may be present. Occasionally the tumor is exophytic, either outwards into the basal cisterns or centrally in the 4th ventricle. Usually the tumor is homogenous pre-treatment, however in a minority of patients areas of necrosis may be present.

  • T1: Decreased intensity
  • T2: Heterogeneously increased
  • T1 C+ (Gd): Usually minimal (can enhance post radiotherapy)
  • Diffusion weighted imaging (DWI): Usually normal, occasionally mildly restricted
  • Tectal glioma

Typically the tumors demonstrate expansion of the tectal plate by a solid nodule of tissue.

  • T1: Iso to slightly hypointense to grey matter 1-3
  • T2: Hyperintense to grey matter
  • T1 C+ (Gd): usually no enhancement

With time the mass can develop small cystic spaces (sometimes associated with neurological deficits) or calcification 3.

Higher grade tumours tend to be larger and tend to enhance more vividly

References

  1. Imaging of Brainstem gliomas. Dr Yuranga Weerakkody and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/brainstem-glioma

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