Rhabdomyosarcoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Medical Therapy

All patients with rhabdomyosarcoma require multimodality therapy with systemic chemotherapy, in conjunction with either surgery, radiation therapy (RT), or both modalities to maximize local tumor control.

Chemotherapy

Chemotherapy may be given as neoadjuvant chemotherapy or adjuvant chemotherapy. Common agents include:

• Vincristine
• Cyclophosphamide
• Dactinomycin
• Adriamycin
• Ifosfamide
• VP-16

Raditherapy

• External beam radiation is used in some cases of rhabdomyosarcoma.