Gliomatosis cerebri pathophysiology

	Gliomatosis cerebri Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Gliomatosis cerebri may be classified into primary (de novo) or secondary, with the latter as a result from the spreading of a more focal glioma.
According to WHO classification of brain tumors, gliomatosis cerebri is classified into grade 2 or grade 3 tumors.

Gliomatosis cerebri may be associated with:

On gross pathology, gliomatosis cerebri is characterized by:

Diffuse, usually astrocytic growth pattern
Involves at least three cerebral lobes
Bilateral involvement of the cerebral hemispheres, deep gray matter, brainstem, or cerebellum