Neuroblastoma laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

An elevated concentration of blood and urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) is suggestive of neuroblastoma.

Laboratory Findings

Blood Tests

• Reduced Hemoglobin level
• Elevated ferritin level
• Elevated catecholamine levels
• Elevated dopamine level
• Elevated vanillylmandelic acid (VMA) level
• Elevated Homovanillic acid (HVA) level
• Elevated lactate dehydrogenase level (>1500 U/ml)
• Elevated neuron-specific enolase level(>100 ng/ml)

Urinalysis

• Elevated concentration of catecholamine levels
• Elevated Vanillylmandelic acid (VMA) level
• Elevated Homovanillic acid (HVA) level