Hamartoma overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
A hamartoma (from Greek hamartion “bodily defect”) is a focal malformation that resembles a neoplasm in the tissue of its origin. This is not a malignant tumor, and it grows at the same rate as the surrounding tissues. It is composed of tissue elements normally found at that site but that are growing in a disorganized fashion.[1]They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason (incidentaloma).
Historical Perspective
Classification
Pathophysiology
Causes
Hamartomas may be caused by an abnormal formation of normal tissue.[2]
Differentiating Harmartoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
If left untreated, hamartomas normally grow slowly and may progress to develop a considerable size, however pulmonary hamartomas have low or no malignant potential. Nevertheless, it is essential to rule out the presence of cancer. Common complications of hamartomas will depend on the location and size. Prognosis is generally regraded as excellent.[3]
Diagnosis
Staging | History and Symptoms | Physical Examination | Laboratory Findings | Biopsy | Chest X ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost Effectiveness of Therapy | Future or Investigational Therapies
Case Studies
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 147. ISBN 978-1416054542.
- ↑ Hamartomas. Wikipedia https://en.wikipedia.org/wiki/Hamartoma Accessed on December 08, 2015
- ↑ Marchiori E, Souza AS, Franquet T, Müller NL (2005). "Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT". AJR Am J Roentgenol. 184 (1): 273–82. doi:10.2214/ajr.184.1.01840273. PMID 15615988.