Ankylosing spondylitis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS).There are certain blood tests that can check for markers of inflammation.Most of the time patients with AS their blood is tested for the HLA-B27 gene, but again most people who are positive for that gene don't have ankylosing spondylitis.Other laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.
Laboratory Findings
- There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS) and most the tests are non-specific.
- Human leukocyte antigen (HLA)-B27 is positive in most the patients, but not invariably so.[1]
- laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.
Increase in:
- C-reactive protein (CRP) and
- Erythrocyte sedimentation rate (ESR).
References
- ↑ de Winter JJ, van Mens LJ, van der Heijde D, Landewé R, Baeten DL (September 2016). "Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis". Arthritis Res. Ther. 18: 196. doi:10.1186/s13075-016-1093-z. PMC 5009714. PMID 27586785.