Folate deficiency laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Laboratory Findings
First line investigations include the following:
- Examination of peripheral blood smear : Macrocytic anemia and hypersegmented neutrophils are classically seen in folate deficiency. Anisocytosis and poikilocytosis can also be observed.
- Complete Blood Count : Low hemoglobin, elevated MCV and MCH, thrombocytopenia, neutropenia.
- Reticulocyte count : Low corrected reticulocyte count which indicates decreased production by the bone marrow.
Reference Range | |
Folic Acid in Serum/Plasma Deficiency | 3.6-15 mg/dl |
Adequate Folic Acid Supply | > 4 ug/l |
Erythrocyte Folic Acid | 120-800 ug/l |