Sideroblastic anemia physical examination

Sideroblastic anemia Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

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Physical Examination

The following physical examination features are suggestive of sideroblastic anemia:

• General - Growth retardation in children
• Vital signs - Hypothermia
• Oral - Lead line on teeth margins
• Skin - Photosensitivity (porphyria), petechiae (myelodysplastic syndrome)
• Eyes - Optic atrophy (associated with DIDMOAD syndrome)
• Neurologic - Ataxia, diminished deep-tendon reflexes, incoordination
• Cardiovascular - Fatigue
• Respiratory - Dyspnea
• Abdominal - Splenomegaly
• Musculoskeletal - Muscular weakness
• Genitourinary - Pink staining of diapers from porphyrins in urine