Myasthenia gravis laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Laboratory Findings
Laboratory findings consistent with the diagnosis of myasthenia gravis include:
Acetylcholine receptor antibodies:
One of the most important steps in confirming the diagnosis of myasthenia gravis is detecting AchR-Ab. About 85 percent of patients with generalized myasthenia gravis are seropositive for this Abs.(8-9) these antybodies are specific for myasthenia gravis but in rare cases we have false positive such as lambert-eaton, motor neuron disease, polymyositis(10-15-16) and even in the disease not related to myasthenia such as primary biliary cholangitis and systemic lupus erythematosus.(17-18) since the patient can become seronegative after immune modulating therapy, this test should be done before treatment. (12)