Neutropenia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and Symptoms
Neutropenia can go undetected until the patient develops secondary, and often severe, infections or sepsis. Some common infections can take an unexpected course in neutropenic patients; formation of pus, for example, can be notably absent, as this requires circulating neutrophil granulocytes. History should focus on symptoms suggestive of malignancy or infections, patient or family history of autoimmune or immunodeficiency disorders, risk factors for infections including HIV and hepatitis, and any unusual dietary practices or history of bariatric surgery. Medications should be reviewed with particular attention to chemotherapeutics, antibiotics, antiepileptics, and psychoactive drugs as well as documenting any new medications started within the preceding few months.
Common presenting symptoms in neutropenic patients include:
- Fever
- Frequent infections due to lessened ability to fight bacterial infections
- Mouth ulcers
- Diarrhea
- Burning sensation when urinating
- Unusual redness, pain, or swelling around a wound
- Sore throat
- Shortness of breath
- Shaking chills