Neutropenia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Daniel A. Gerber, M.D. [2]

Overview

At-risk populations include those undergoing cytotoxic chemotherapy or other myelosuppressive medications, however a benign form of mild neutropenia is commonly identified in certain ethnicities (blacks, Yemenites, West Indians, Arab Jordanians). This latter group rarely develops complications from their neutropenia.

Risk Factors

• Medications
• Cytotoxic chemotherapy
• Hematologic malignancies
• Autoimmune disorders
• Infections
• Hemodialysis
• Radiation therapy
• Vitamin deficiencies e.g. folate, Vitamin B12
• Black, Yemenite, West Indian, or Arab Jordanian ethnicity