Spontaneous bacterial peritonitis screening
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]
Overview
Screening
- Leukocyte esterase strip calibrated to an ascitic fluid neutrophil count 250/microl is an effective screening tool when the strip turns to any hue of brown at 3 min. [1]
- Fecal calprotectin is a useful screening parameter for spontaneous bacterial peritonitis in cirrhosis. It is helpful in grading the severity of hepatic encephalopathy.[2][3]
References
- ↑ Mendler MH, Agarwal A, Trimzi M, Madrigal E, Tsushima M, Joo E; et al. (2010). "A new highly sensitive point of care screen for spontaneous bacterial peritonitis using the leukocyte esterase method". J Hepatol. 53 (3): 477–83. doi:10.1016/j.jhep.2010.04.011. PMID 20646775.
- ↑ Gundling F, Schmidtler F, Hapfelmeier A, Schulte B, Schmidt T, Pehl C; et al. (2011). "Fecal calprotectin is a useful screening parameter for hepatic encephalopathy and spontaneous bacterial peritonitis in cirrhosis". Liver Int. 31 (9): 1406–15. doi:10.1111/j.1478-3231.2011.02577.x. PMID 22093455.
- ↑ Fernandes, Samuel Raimundo; Santos, Patrícia; Fatela, Narcisa; Baldaia, Cilénia; Tato Marinho, Rui; Proença, Helena; Ramalho, Fernando; Velosa, José (2016). "Ascitic Calprotectin is a Novel and Accurate Marker for Spontaneous Bacterial Peritonitis". Journal of Clinical Laboratory Analysis. 30 (6): 1139–1145. doi:10.1002/jcla.21994. ISSN 0887-8013.