Congenital rubella syndrome physical examination
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]
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Overview
Congenital rubella syndrome is characterized by triad of sensorineural deafness, eye abnormalties (cataracts, retinopathy) and heart defects (PDA).
Physical Examination
Organ System | Findings | Suggestive of | ||
---|---|---|---|---|
General Appearance | Low birth weight | |||
Skin | Skin lesions of several sizes (petechiae and purpura) | Thrombocytopenic purpura | ||
Yellow discoloration of the skin and mucous membranes | Obstructive jaundice | |||
Eyes | Clouding of the corneas | Cataracts | ||
Congenital glaucoma | ||||
Pigmentary retinopathy | ||||
Yellow discoloration of the sclera | Obstructive jaundice | |||
Ears | Sensorineural hearing loss | |||
Heart | Holosystolic murmur, best heard at the left lower sternal border | Ventricular septal defect (VSD) | ||
Continuous, machinery murmur, best heard at the left infraclavicular area | Patent ductus arteriosus (PDA) | |||
|
Coarctation of the aorta | |||
Pulmonary artery stenosis | ||||
Abdomen | Hepatosplenomegaly (HSM) | |||
Neurological | Small head circumference | Microcephaly | ||
Encephalitis | ||||
Mental retardation |
References
- ↑ De Santis M, Cavaliere AF, Straface G, Caruso A (2006). "Rubella infection in pregnancy". Reprod. Toxicol. 21 (4): 390–8. doi:10.1016/j.reprotox.2005.01.014. PMID 16580940.
- ↑ Lambert N, Strebel P, Orenstein W, Icenogle J, Poland GA (2015). "Rubella". Lancet. 385 (9984): 2297–307. doi:10.1016/S0140-6736(14)60539-0. PMC 4514442. PMID 25576992.
- ↑ Ajij M, Nangia S, Dubey BS (2014). "Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis". J Clin Diagn Res. 8 (12): PD03–4. doi:10.7860/JCDR/2014/10271.5293. PMC 4316306. PMID 25654000.
- ↑ Bullens D, Smets K, Vanhaesebrouck P (2000). "Congenital rubella syndrome after maternal reinfection". Clin Pediatr (Phila). 39 (2): 113–6. PMID 10696549.
- ↑ Yazigi A, De Pecoulas AE, Vauloup-Fellous C, Grangeot-Keros L, Ayoubi JM, Picone O (2017). "Fetal and neonatal abnormalities due to congenital rubella syndrome: a review of literature". J. Matern. Fetal. Neonatal. Med. 30 (3): 274–278. doi:10.3109/14767058.2016.1169526. PMID 27002428.