Ascariasis natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]
Overview
Ascariasis is often asymptomatic.[1] Complications may arise when adult worms move to certain organs such as the bile duct, pancreas, or appendix.[1] A high worm burden can also result in complications such as intestinal obstruction.[2]
Natural History
The majority of people infected with Ascaris are asymptomatic although greater than 15% can experience some type of morbidity.[1]
Complications
Complications of ascariasis include the following:[3][2][4]
- Biliary duct disease
- Hepatic abscess
- Intestinal obstruction associated with perforation, volvulus, and intussusception
- Peritonitis
- Pancreatitis
- Acute appendicitis
- Malabsorption and growth impairment from chronic infection with Ascaris lumbricoides
- Interstitial nephritis and acute renal failure (rare)
- Acute eosinophilic pneumonia resulting in respiratory distress (rare)
Prognosis
The prognosis is good and most cases of ascariasis can be asymptomatic, but mortality can sometimes be as high as 60,000 per year in symptomatic patients.[1]
References
- ↑ 1.0 1.1 1.2 1.3 Durand, Marlene (2015). "Chapter 288:Intestinal Nematodes (Roundworms)". Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases Updated Edition, Eighth Edition. Elsevier. pp. 3199–3207. ISBN 978-1-4557-4801-3.
- ↑ 2.0 2.1 Kliegman, Robert; Stanton, Bonita; St. Geme, Joseph; Schor, Nina (2016). "Chapter 291:Ascariasis (Ascaris lumbricoides)". Nelson Textbook of Pediatrics Twentieth Edition. Elsevier. pp. 1733–1734. ISBN 978-1-4557-7566-8.
- ↑ Ferri, Fred (2017). "Chapter:Ascariasis". Ferri's Clinical Advisor 2017. Elsevier. pp. 117–117. ISBN 978-0-3232-8048-8.
- ↑ Kim, Kami; Weiss, Louis; Tanowitz, Herbert (2016). "Chapter 39:Parasitic Infections". Murray and Nadel's Textbook of Respiratory Medicine Sixth Edition. Elsevier. pp. 682–698. ISBN 978-1-4557-3383-5.