Antiphospholipid syndrome secondary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Secondary Prevention
Long term anticoagulation
Anticoagulation for venous thrombosis Anticoagulation for arterial thrombosis
Reduction of reversible risk factors
Randomized controlled trials have addressed the secondary prevention of thromboses. These trials showed:
A systematic review has summarized the research.[3]
References
- ↑ Crowther MA, Ginsberg JS, Julian J, Denburg J, Hirsh J, Douketis J; et al. (2003). "A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome". N Engl J Med. 349 (12): 1133–8. doi:10.1056/NEJMoa035241. PMID 13679527. Review in: ACP J Club. 2004 Mar-Apr;140(2):38
- ↑ Finazzi G, Marchioli R, Brancaccio V, Schinco P, Wisloff F, Musial J; et al. (2005). "A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS)". J Thromb Haemost. 3 (5): 848–53. doi:10.1111/j.1538-7836.2005.01340.x. PMID 15869575.
- ↑ Ruiz-Irastorza G, Hunt BJ, Khamashta MA (2007). "A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies". Arthritis Rheum. 57 (8): 1487–95. doi:10.1002/art.23109. PMID 18050167.