Toxic shock syndrome secondary prevention
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]
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Overview:
Secondary prevention strategies following toxic shock syndrome (TSS) include chemoprophylaxis for invasive group A streptococcus or staphylococcus carriers. Although it is still not certain to be helpful.
Secondary Prevention
- One of the major complications of toxic shock syndrome is that it increase the risk of disease re-currence. This condition can be controlled by chemoprophylaxis of patients with a past medical history of TSS. However, there is limited data concerning chemoprophylaxis for severe invasive group A streptococcal or staphylococcal infections.
- Also researchers advice not to continue tampon usage after a TSS, to prevent the recurrence of the disease.
- Several antibiotic regimens have been successful in eradicating group A streptococcus from the pharynx of chronic carriers i.e.,
- Rifampin plus intramuscular benzathine penicillin or
- A 10-day course of a second-generation cephalosporin or
- Clindamycin)