Graft-versus-host disease other diagnostic studies
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Graft-versus-host disease |
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Differentiating Graft-versus-host disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Other Diagnostic Studies
The diagnosis of GvhD can be made at the histologic level via tissue biopsy. Biopsies of the suspected organs involved can aid in the diagnosis. A skin biopsy, for example, will show findings such as vacuolar interface dermatitis. The sensitivities of tissue biopsy is somewhat limited though, and nearly 40% of cases can be missed.[1] Biopsies of the upper GI tract can be achieved via endoscopy, and biopsies of the lower GI tract can be achieved via colonoscopy or flexible sigmoidoscopy.
References
- ↑ Qian L, Wu Z, Shen J (2013). "Advances in the treatment of acute graft-versus-host disease". J Cell Mol Med. 17 (8): 966–75. doi:10.1111/jcmm.12093. PMC 3780546. PMID 23802653.