Systemic lupus erythematosus causes
|
Systemic lupus erythematosus Microchapters |
|
Differentiating Systemic lupus erythematosus from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Systemic lupus erythematosus causes On the Web |
|
American Roentgen Ray Society Images of Systemic lupus erythematosus causes |
|
Directions to Hospitals Treating Systemic lupus erythematosus |
|
Risk calculators and risk factors for Systemic lupus erythematosus causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
There are no established causes for systemic lupus erythematosus. Common causes of systemic lupus erythematosus include genetic predisposition, auto-immune disease, and drugs. Less common causes of systemic lupus erythematosus include environmental factors,and exposure to ultraviolet (UV) light.
Causes
- Genetic predisposition 8749564
- HLA class polymorphism
- Complement genes
- Female sexual gene due to high levels of estrogen and prolactin
- Auto-immune disease 7656468
- Environmental triggers 12464374
- Infections
- Exposure to ultraviolet (UV) light
- Can exacerbate or induce systemic manifestations of SLE
- Drug-induced lupus
- Acebutolol
- Adalimumab
- Anastrozole
- Bupropion
- Captopril
- Cilazapril
- Cinnarizine/thiethylperazine
- Diltiazem
- Docetaxel
- Doxorubicin
- D-penicillamine
- Etanercept
- Gemcitabine
- Glyburide
- Golimumab
- Griseofulvin
- Hydrochlorothiazide
- Infliximab
- Interferon-alpha
- Interferon-beta
- Oxprenolol
- Phenytoin
- Lamotrigine
- Lansoprazole
- Leflunomide
- Leuprorelin
- Naproxen
- Nifedipine
- Nitrendipine
- Omeprazole
- Paclitaxel
- Pantoprazole
- Piroxicam
- Pravastatin
- Ranitidine
- Simvastatin
- Spironolactone
- Tamoxifen
- Terbinafine
- Ticlopidine
- Verapamil
- sulfonamide containing antibiotics, have been associated with SLE exacerbations and should be avoided