Cretinism medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The mainstay of treatment for cretinism is thyroid hormone replacement therapy. Levothyroxine (L-T4) is administrated orally to patients with cretinism.

Medical Therapy

• Patients with cretinism are treated with thyroid hormone replacement therapy.
• Endocrine society recommended with the appropriate quick initiation of levothyroxine as the mainstay treatment of cretinism.
• Levothyroxine:
  • Life long synthetic levothyroxine (L-T4) is used to treat the cretinism.
  • Dosage:  10–15 μg/kg per day orally