Prolactinoma classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2], Anmol Pitliya, M.B.B.S. M.D.[3]
Overview
Prolactinoma can be classified based upon either size or local invasion. Based on size, a prolactinoma can be classified as a microprolactinoma (<10 mm diameter) or macroprolactinoma (>10 mm diameter).
Classification
Prolactinoma may be classified based on either size or local invasion.
| Classification of prolactinoma | |||
|---|---|---|---|
| Classification basis | Type/Grade | Criteria | |
| Classification based on size | Microprolactinoma | <10 mm diameter | |
| Macroprolactinoma | >10 mm diameter | ||
| Classificatioin based on local invasion | Size and Invasion | 0 | Normal pituitary appearance |
| I | Enclosed within the sella turcica, microadenoma smaller than 10 mm | ||
| II | Enclosed within the sella turcica, macroadenoma 10 mm or larger | ||
| III | Invasive, locally, into the sella turcica | ||
| IV | Invasive, diffusely, into the sella turcica | ||
| Grading scheme for suprasellar extensions | A | 0 to 10 mm suprasellar extension occupying the suprasellarcistern | |
| B | 10 mm to 20 mm extension and elevation of the third ventricle | ||
| C | 20 mm to 30 mm extension occupying the anterior of the third ventricle | ||
| D | A larger than 30 mm extension, beyond the foramen of Monro, or Grade C with lateral extensions | ||
Classification based on size
Based on size, a prolactinoma can be classified as:[1]
- Microprolactinoma (<10 mm diameter)
- Macroprolactinoma (>10 mm diameter)
Classificatioin based on local invasion
The classification for pituitary adenomas is as follows:[2][3][4]
- 0: Normal pituitary appearance
- I: Enclosed within the sella turcica, microadenoma smaller than 10 mm
- II: Enclosed within the sella turcica, macroadenoma 10 mm or larger
- III: Invasive, locally, into the sella turcica
- IV: Invasive, diffusely, into the sella turcica
The grading scheme for suprasellar extensions is as follows:
- A: 0 to 10 mm suprasellar extension occupying the suprasellarcistern
- B: 10 mm to 20 mm extension and elevation of the third ventricle
- C: 20 mm to 30 mm extension occupying the anterior of the third ventricle
- D: A larger than 30 mm extension, beyond the foramen of Monro, or Grade C with lateral extensions
References
- ↑ Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE (2004). "The prevalence of pituitary adenomas: a systematic review". Cancer. 101 (3): 613–9. doi:10.1002/cncr.20412. PMID 15274075.
- ↑ "Pituitary Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute".
- ↑ Yeh PJ, Chen JW (1997). "Pituitary tumors: surgical and medical management". Surg Oncol. 6 (2): 67–92. PMID 09436654.
- ↑ Hardy J: Transsphenoidal surgery of hypersecreting pituitary tumors. In: Kohler PO, Ross GT, eds.: Diagnosis and treatment of pituitary tumors: proceedings of a conference sponsored jointly by the National Institute of Child Health and Human Development and the National Cancer Institute, January 15-17, 1973, Bethesda, Md. Amsterdam, The Netherlands: Excerpta medica, 1973, pp 179-98