Vitamin D deficiency classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
According to the Global Consensus Recommendations on Prevention and Management of Nutritional Rickets and the Institute of Medicine (IOM), vitamin D deficiency is classified into two groups of deficient and Insufficient based on serum 25(OH)D level. It could be further classified as mild, moderate, and severe deficiency. Another classification scheme is based on etiology of vitamin D deficiency which classify it as acquired or inherited.
Classification
- According to the Global Consensus Recommendations on Prevention and Management of Nutritional Rickets and the Institute of Medicine (IOM), vitamin D deficiency is classified into two groups of deficient and Insufficient based on serum 25(OH) vit D3 level.[1]
| Serum 25(OH)D Concentrations and Health[2] | |||
|---|---|---|---|
| Definition | Vitamin D serum level | Health status | |
| nmol/L | ng/mL | ||
| Sufficient | ≥50 | ≥20 | Generally considered adequate for bone and overall health in healthy individuals |
| Insufficient | 30 to <50 | 12 to <20 | Generally considered inadequate for bone and overall health in healthy individuals |
| Deficient | <30 | <12 | Associated with vitamin D deficiency, leading to rickets in infants and children and osteomalacia in adults |
- Australian Family Physician classified vitamin D deficiency into three groups based on serum level of 25(OH) vit D.[3]
| Serum 25(OH)D Concentrations and level of deficiency[4] | |
|---|---|
| Severity | Vitamin D serum level (nmol/L) |
| Severe | <12.5 |
| Moderate | 12.5–29 |
| Mild | 30–50 |
- Vitamin D deficiency may be classified into two main groups of acquired or inherited based on the etiology.
References
- ↑ Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, et al., editors. Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); 2011. Available from: https://www.ncbi.nlm.nih.gov/books/NBK56070/ doi: 10.17226/13050
- ↑ "Vitamin D — Health Professional Fact Sheet".
- ↑ Nowson CA, McGrath JJ, Ebeling PR, Haikerwal A, Daly RM, Sanders KM, Seibel MJ, Mason RS (2012). "Vitamin D and health in adults in Australia and New Zealand: a position statement". Med. J. Aust. 196 (11): 686–7. PMID 22708765.
- ↑ "RACGP - Vitamin D and the musculoskeletal health of older adults". Australian Family Physician. 2012. pp. 92–99.