Toxic megacolon historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Historical Perspective

Discovery

• Toxic megacolon was first discovered by Marshak and Lester in 1950.
• In 1950, Marshak was the first to discover the association between Clostridium difficile and the development of toxic megacolon.ef>