Hepatorenal syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]


Overview

The cause of Hepatorenal syndrome [HS] is deteriorating function of liver.

Causes

The cause of Hepatorenal syndrome [HS] is deteriorating function of liver. It happens in following context:[1][2][3]

  • Liver function goes down which causes portal hypertension
  • Portal hypertension causes arterial vasodilatation in the splanchnic circulation
  • Arterial vasodilatation in the splanchnic circulation is due to Nitirc oxide
  • Arterial vasodilatation in the splanchnic circulation causes decreased blood flow to renal tissue
  • Renal tissue is prone to hypo-oxymeia

References

  1. Pillebout E (2014). "[Hepatorenal syndrome]". Nephrol Ther. 10 (1): 61–8. doi:10.1016/j.nephro.2013.11.005. PMID 24388293.
  2. Egerod Israelsen M, Gluud LL, Krag A (2015). "Acute kidney injury and hepatorenal syndrome in cirrhosis". J Gastroenterol Hepatol. 30 (2): 236–43. doi:10.1111/jgh.12709. PMID 25160511.
  3. Prabhu MV, Sukanya B, Santosh Pai BH, Reddy S (2014). "[The hepatorenal syndrome - a review]". G Ital Nefrol. 31 (3). PMID 25030015.

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