Autoimmune hepatitis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: :Manpreet Kaur, MD [2]
Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal among patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name].
Laboratory Findings
Following laboratory tests are used to diagnose autoimmune hepatitis:
- Liver function tests
- Alkaline phosphatase
- Antibody assays
- Serum protein and immunoglobulins
- Complete blood count and differential count
- Platelet count
- ESR
- Coombs test
- Peripheral blood film
Laboratory findings consistent with the diagnosis of Autoimmune hepatitis include:
- Increased serum aminotransferase levels (1.5-50 times reference values)
- Increased serum immunoglobulin levels, primarily immunoglobulin G (1.2 to 3.0 times normal)
- Seropositive for ANAs, anti-actin, SMAs, LKM-1, anti-liver cytosol 1 (anti-LC1) antibodies, SLA/LP autoantibodies or pANCA
- Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].