Esophageal cancer classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Esophageal cancer may be classified into squamous cell carcinoma or adenocarcinoma based on histology.
Classification
Esophageal cancers are typically carcinomas, which arise from the epithelium, or surface lining of the esophagus. Most esophageal cancers fall into one of two classes [1]
- Squamous cell carcinoma
- Similar to head and neck cancer in their appearance and associated with smoking and alcohol consumption
- Adenocarcinoma
- Make up more than 70% of esophageal cancers
- Often associated with a history of gastroesophageal reflux disease and Barrett's esophagus
References
- ↑ Buas MF, Vaughan TL (2013). "Epidemiology and risk factors for gastroesophageal junction tumors: understanding the rising incidence of this disease". Semin Radiat Oncol. 23 (1): 3–9. doi:10.1016/j.semradonc.2012.09.008. PMC 3535292. PMID 23207041.