Multiple sclerosis causes
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Overview
Causes
Multiple sclerosis may be caused by:
Autoimmunity:
The main hypothesis regarding MS etiology is that it is caused by an autoimmune reaction against central nervous system (CNS). Self reactive T cells which has been activated by a foreign (virus for example) or native factor, will attack the myelin sheath around the neurons. [1] Presents of autoreactive T cells and myelin basic protein-specific CD4+ T cells in the peripheral blood smear of MS patients supports the autoimmune hypothesis.
Genetic:
Infectious:
Degenerative:
References
- ↑ Korn T (2008). "Pathophysiology of multiple sclerosis". J. Neurol. 255 Suppl 6: 2–6. doi:10.1007/s00415-008-6001-2. PMID 19300953.