Lupus nephritis electrocardiogram

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no ECG findings associated with [disease name].

OR

An ECG may be helpful in the diagnosis of [disease name]. Findings on an ECG suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

Electrocardiogram

The most common and important ECG findings associated with systemic lupus erythematosus (SLE) include sinus tachycardia, ST segment changes, and ventricular conduction disturbances. SLE can affect cardiopulmonary system in different ways including pulmonary emboli development, Libman sacks endocarditis, and conduction problems.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

Important ECG findings in SLE patients based on cardiac complication:

Cardiac complication		ECG findings	ECG examples
Cardiomegaly		Increase in QRS amplitude Widened QRS/T angle Left atrial enlargement Left axis deviation	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Libman sacks endocarditis	Heart failure	P wave changes R wave height changes Primary increase Decrease after progression	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Libman sacks endocarditis	Myocardial infarction	Due to emboli ST elevation of 2 mm (0.2 mV) in men or 1.5 mm (0.15 mV) in women in V2–V3 and/or of 1 mm (0.1mV) in 2 contiguous chest leads or limb leads ST depression in at least two precordial leads V1-V4 (suggestive of posterior MI) ST depression in several leads plus ST elevation in lead aVR (suggestive of occlusion of the left main or proximal LAD artery) New left bundle branch block (LBBB)	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Valvular involvement	Mitral valve stenosis	ECG findings suggestive of left atrial enlargement include: Broad and biphasic P wave in lead II (P mitrale) Enlargement of the terminal negative portion of the P wave in VI P wave amplitude >2.5 mm in inferior leads (II, III, AVF) or >1.5 mm in V1/V2 (P pulmonale)	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Valvular involvement	Mitral regurgitation	ECG findings suggestive of left atrial enlargement include: Broad and biphasic P wave in lead II (P mitrale) Enlargement of the terminal negative portion of the P wave in V1 P wave amplitude >2.5 mm in inferior leads (II, III, AVF) or >1.5 mm in V1/V2 (P pulmonale) ECG findings suggestive of left ventricular enlargement include: Increased QRS voltage on ECG Strain pattern Inverted check mark pattern to the T wave in the lateral leads	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Arrhythmias	AV Blocks	Incomplete bundle branch block Right bundle branch block Left bundle branch block Left anterior fascicular block Left posterior fascicular block	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Arrhythmias	Supraventricular arrhythmias	Premature atrial complexes (PAC) Atrial fibrillation Atrial flutter	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Pericardial disease	Acute pericarditis	ST segment depression: Always in aVR Frequently in V1 Occasionally in V2 J point in V6 > 25% of the height of the T wave apex Reduced voltage with quasi-specific ST-T waves due to increase in scar tissue, fluid and fibrin The EKG abnormalities vary depending on the stage/severity of the pericarditis	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu
Pericardial disease	Pericardial effusion	Electrical alternans An electrocardiographic phenomenon of alternation of QRS complex amplitude or axis between beats	https://en.wikipedia.org/wiki/Pericardial_effusion Courtesy dedicated to wikipedia
Myocarditis		The ECG findings most commonly seen in myocarditis are: Sinus tachycardia Diffuse T wave inversions ST segment elevation without reciprocal depression Low voltage of the QRS complexes Arrhythmias such as atrial or ventricular ectopic beats, atrial or ventricular tachycardias, and atrial fibrillation	https://en.wikipedia.org/wiki/Myocarditis Courtesy dedicated to wikipedia
Coronary artery disease		Exercise tolerance test findings include: ST segment changes Exercise induced ventricular arrhythmia Hemodynamic changes during the test	http://ecg.utah.edu/img_index Courtesy dedicated to ecg.utah.edu

References

↑ Bourré-Tessier J, Urowitz MB, Clarke AE, Bernatsky S, Krantz MJ, Huynh T, Joseph L, Belisle P, Bae SC, Hanly JG, Wallace DJ, Gordon C, Isenberg D, Rahman A, Gladman DD, Fortin PR, Merrill JT, Romero-Diaz J, Sanchez-Guerrero J, Fessler B, Alarcón GS, Steinsson K, Bruce IN, Ginzler E, Dooley MA, Nived O, Sturfelt G, Kalunian K, Ramos-Casals M, Petri M, Zoma A, Pineau CA (2015). "Electrocardiographic findings in systemic lupus erythematosus: data from an international inception cohort". Arthritis Care Res (Hoboken). 67 (1): 128–35. doi:10.1002/acr.22370. PMID 24838943.
↑ Tsunakawa H, Miyamoto N, Kawabata M, Mashima S (1993). "[Electrocardiogram in heart failure]". Nippon Rinsho (in Japanese). 51 (5): 1222–32. PMID 8331790.
↑ Maganti K, Rigolin VH, Sarano ME, Bonow RO (2010). "Valvular heart disease: diagnosis and management". Mayo Clin Proc. 85 (5): 483–500. doi:10.4065/mcp.2009.0706. PMC 2861980. PMID 20435842.
↑ TROUNCE JR (1952). "The electrocardiogram in mitral stenosis". Br Heart J. 14 (2): 185–92. PMC 479442. PMID 14916061.
↑ Nakashima H, Honda Y, Katayama T (1994). "Serial electrocardiographic findings in acute myocarditis". Intern. Med. 33 (11): 659–66. PMID 7849377.
↑ Feldman AM, McNamara D (2000). "Myocarditis". N Engl J Med. 343 (19): 1388–98. doi:10.1056/NEJM200011093431908. PMID 11070105.
↑ Troughton RW, Asher CR, Klein AL (2004). "Pericarditis". Lancet. 363 (9410): 717–27. doi:10.1016/S0140-6736(04)15648-1. PMID 15001332.
↑ Spodick DH (2003). "Acute pericarditis: current concepts and practice". JAMA. 289 (9): 1150–3. doi:10.1001/jama.289.9.1150. PMID 12622586.

Template:WH Template:WS

[pmid24838943-1] Bourré-Tessier J, Urowitz MB, Clarke AE, Bernatsky S, Krantz MJ, Huynh T, Joseph L, Belisle P, Bae SC, Hanly JG, Wallace DJ, Gordon C, Isenberg D, Rahman A, Gladman DD, Fortin PR, Merrill JT, Romero-Diaz J, Sanchez-Guerrero J, Fessler B, Alarcón GS, Steinsson K, Bruce IN, Ginzler E, Dooley MA, Nived O, Sturfelt G, Kalunian K, Ramos-Casals M, Petri M, Zoma A, Pineau CA (2015). "Electrocardiographic findings in systemic lupus erythematosus: data from an international inception cohort". Arthritis Care Res (Hoboken). 67 (1): 128–35. doi:10.1002/acr.22370. PMID 24838943.

[pmid8331790-2] Tsunakawa H, Miyamoto N, Kawabata M, Mashima S (1993). "[Electrocardiogram in heart failure]". Nippon Rinsho (in Japanese). 51 (5): 1222–32. PMID 8331790.

[pmid20435842-3] Maganti K, Rigolin VH, Sarano ME, Bonow RO (2010). "Valvular heart disease: diagnosis and management". Mayo Clin Proc. 85 (5): 483–500. doi:10.4065/mcp.2009.0706. PMC 2861980. PMID 20435842.

[pmid14916061-4] TROUNCE JR (1952). "The electrocardiogram in mitral stenosis". Br Heart J. 14 (2): 185–92. PMC 479442. PMID 14916061.

[pmid7849377-5] Nakashima H, Honda Y, Katayama T (1994). "Serial electrocardiographic findings in acute myocarditis". Intern. Med. 33 (11): 659–66. PMID 7849377.

[pmid110701052-6] Feldman AM, McNamara D (2000). "Myocarditis". N Engl J Med. 343 (19): 1388–98. doi:10.1056/NEJM200011093431908. PMID 11070105.

[troughton-7] Troughton RW, Asher CR, Klein AL (2004). "Pericarditis". Lancet. 363 (9410): 717–27. doi:10.1016/S0140-6736(04)15648-1. PMID 15001332.

[spodick-8] Spodick DH (2003). "Acute pericarditis: current concepts and practice". JAMA. 289 (9): 1150–3. doi:10.1001/jama.289.9.1150. PMID 12622586.

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Lupus nephritis electrocardiogram

Overview

Electrocardiogram

Important ECG findings in SLE patients based on cardiac complication:

References

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