Multiple sclerosis differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
- Overview
Differentiating multiple sclerosis from other diseases
Multiple sclerosis must be differentiated from other diseases that can mimic this disease clinically or radiologically such as:
Inflammatory conditions:
- systemic lupus erythematosus
- Sjögren’s syndrome
- Vasculitis
- Behçet’s disease
- sarcoidosis
Infections:
- Lyme disease
- syphilis
- Progressive multifocal leukoencephalopathy
- HTLV-1 infection
- Herpes zoster
Metabolic and genetic disorders:
- Vitamin B12 deficiency
- Lysosomal disorders
- Adrenoleukodystrophy
- Mitochondrial disorders
- Clinically defined genetic disorders