Behçet's disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Cafer Zorkun, M.D., Ph.D. [2]
Overview
Epidemiology and Demographics
Behçet syndrome is more common (and often more severe) along the ancient silk road, which extends from eastern Asia to the Mediterranean [1]. It is most common in Turkey (80 to 370 cases per 100,000), while the prevalence ranges from 13.5 to 20 per 100,000 in Japan, Korea, China, Iran, and Saudi Arabia [1]. Prevalence in Paris, France in 2003 was 7.1 per 100,000, with rates of 2.4 per 100,000 in those of European ancestry, of 34.6 per 100,000 in those of North African ancestry, and of 17.5 per 100,000 in those of Asian ancestry [2,3]. Estimates of prevalence in the United States and Europe have ranged from 0.12 to 7.5 per 100,000. Analysis of residents of Olmsted County, Minnesota over a 45-year period identified a prevalence of 5.2 per 100,000 [4]. It is somewhat more common in men in the eastern Mediterranean area and in women in north European countries, and it typically affects young adults 20 to 40 years of age [1]. Immigrant and refugee populations from areas of high Behçet syndrome prevalence demonstrate increased risk of disease development [5].
Incidence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The prevalence of behcet disease is approximately 80 to 370 per 100,000 individuals in Turkey. [1]
- The prevalence of behcet disease is approximately 13.5 to 20 per 100,000 individuals in Iran, Japan, Korea, China and Saudi Arabia. [1]
- The prevalence of behcet disease is approximately 7.1 per 100,000 individuals in Paris, France.[2]
- The prevalence of behcet disease is approximately 2.4 per 100,000 individuals in European ancestry[2]
- The prevalence of behcet disease is approximately 34.6 per 100,000 individuals in North African ancestry[2]
- The prevalence of behcet disease is approximately 17.5 per 100,000 individuals in Asian ancestry[2]
- The prevalence of behcet disease is approximately 0.12 to 7.5 per 100,000 individuals in the United States. [3]
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Chronic disease name] is usually first diagnosed among [age group].
- Behcet disease commonly affects young adults 20 to 40 years of age.[4]
Race
- There is no racial predilection to [disease name].
- Behcet disease usually affects individuals of the race. [Race 2] individuals are less likely to develop [disease name].
Gender
- Behcet disease is more common in men in Mediterranean area and more common in women in north European countries.
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of behcet disease cases are reported along the ancient silk road ( from eastern Asia to the Mediterranean)[1]
- Behcet disease is most common in Trukey.
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 Sakane T, Takeno M, Suzuki N, Inaba G (October 1999). "Behçet's disease". N. Engl. J. Med. 341 (17): 1284–91. doi:10.1056/NEJM199910213411707. PMID 10528040.
- ↑ 2.0 2.1 2.2 2.3 Mahr A, Belarbi L, Wechsler B, Jeanneret D, Dhote R, Fain O, Lhote F, Ramanoelina J, Coste J, Guillevin L (December 2008). "Population-based prevalence study of Behçet's disease: differences by ethnic origin and low variation by age at immigration". Arthritis Rheum. 58 (12): 3951–9. doi:10.1002/art.24149. PMID 19035493.
- ↑ Calamia KT, Wilson FC, Icen M, Crowson CS, Gabriel SE, Kremers HM (May 2009). "Epidemiology and clinical characteristics of Behçet's disease in the US: a population-based study". Arthritis Rheum. 61 (5): 600–4. doi:10.1002/art.24423. PMC 3024036. PMID 19405011.
- ↑ Sakane T, Takeno M, Suzuki N, Inaba G (October 1999). "Behçet's disease". N. Engl. J. Med. 341 (17): 1284–91. doi:10.1056/NEJM199910213411707. PMID 10528040.