Minimal change disease other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Renal biopsy may be helpful in the diagnosis of minimal change disease.

Other Diagnostic Studies

• Renal biopsy may be helpful in the diagnosis of minimal change disease.
• Within four weeks of treatment with steroid therapy most of the patients with minimal change disease (MCD) will respond positively.
• Before considering renal biopsy steroid therapy can be initiated in patients who fulfill the following criteria because of the invasive process of the biopsy.
  • Age
    • Patients must be older than 1 year and less than 12 years.
  • Normal complement levels
  • No signs of hypertension, gross hematuria, or a marked increase in serum creatinine