Mixed connective tissue disease other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Pulmonary function test may be helpful in the diagnosis of interstitial lung disease as a complication of MCTD. Findings suggestive of interstitial lung disease include significantly lower DLCO values in the active pulmonary stage and restrictive ventilatory defect (reduction of FEV1 and total lung capacity).
Other Diagnostic Studies
Pulmonary function test
- Pulmonary function test may be helpful in the diagnosis of interstitial lung disease as a complication of MCTD. Findings suggestive of interstitial lung disease include:[1][2]
- DLCO values is significantly lower in the active pulmonary stage (most sensitive test for predicting the presence of fibrosing alveolitis)
- Restrictive ventilatory defect (reduction of FEV1 and total lung capacity)
References
- ↑ Bodolay E, Szekanecz Z, Dévényi K, Galuska L, Csípo I, Vègh J, Garai I, Szegedi G (May 2005). "Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD)". Rheumatology (Oxford). 44 (5): 656–61. doi:10.1093/rheumatology/keh575. PMID 15716315.
- ↑ Gutsche M, Rosen GD, Swigris JJ (September 2012). "Connective Tissue Disease-associated Interstitial Lung Disease: A review". Curr Respir Care Rep. 1: 224–232. doi:10.1007/s13665-012-0028-7. PMC 3486427. PMID 23125954.