Methemoglobinemia classification

Methemoglobinemia Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

Congenital (Hereditary) Methemoglobinemia

There are three main congenital conditions that lead to methemoglobinemia:

1. Cytochrome b5 reductase deficiency and pyruvate kinase deficiency

2. G6PD deficiency

3. Presence of abnormal hemoglobin (Hb M)

Acquired or Acute Methemoglobinemia

The most common causes are different oxidant drugs, toxins and chemicals.