Minimal change disease risk factors
Overview
The cause of minimal change disease has not been identified or idiopathic.Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli) .But secondary causes may be due to Drugs,Toxins,Infection and Tumor .
Common Causes
Common risk factors in the development of minimal change disease include:[1]
- Children within the Age >1 year but <8 years
- Hodgkin lymphoma
- leukemia
- Recent viral illness
- Toxins like Mercury, bee stings, fire coral exposure are one of the causes for minimal change disease.
- Drugs like
- Salazopyrin
- Mercury
- Tiopronin
- Lithium
- D-penicillamine
- Gold
- Tyrosine-kinase inhibitor
Less Common Causes
Less common causes of minimal change disease include:
- Hepatitis B or C infection
- low birth weight (LBW)
- Hematopoietic stem cell transplantation
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References
- ↑ Iijima, Kazumoto; Hamahira, Kiyoshi; Tanaka, Ryojiro; Kobayashi, Akiko; Nozu, Kandai; Nakamura, Hajime; Yoshikawa, Norishige (2002). "Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome". Kidney International. 61 (5): 1801–1805. doi:10.1046/j.1523-1755.2002.00303.x. ISSN 0085-2538.