Minimal change disease diagnostic study of choice
Overview
The diagnostic study of choice for minimal change disease is renal biopsy.
Diagnostic Study of choice
- The diagnostic study of choice for minimal change disease is renal biopsy.[1]
- With four weeks of treatment with steroid therapy, most of the patients with minimal change disease (MCD) will respond positively.
- Before considering renal biopsy steroid therapy can be initiated in patients who fulfill the following criteria because of the invasive process of the biopsy.
- Patients must be older than 1 year and less than 12 years.
- Normal complement levels No signs of hypertension, gross hematuria, or a marked increase in serum creatinine.
- By following this protocol in patients with minimal change disease we can avoid unnecessary invasive approach in almost 80% of the patients.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.