Lead poisoning laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.

Overview

An elevated concentration of venous blood lead levels is diagnostic of lead poisoning.

Laboratory Findings

  • Laboratory findings consistent with the diagnosis of lead poisoning include:
    • Basophilic stippling of red blood cells
    • Iron deficiency anemia (microcytosis and hypochromia)
    • Elevated venous blood lead levels
    • K-fluorescent X-ray metering can measure bone-lead.

Shown below is an image depicting basophilic stippling in a blood smear of a patient with lead poisoning.
Basophilic stippling in a blood smear of a patient with lead poisoning

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