Fibromuscular dysplasia epidemiology and demographics

Fibromuscular dysplasia Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Fibromuscular dysplasia from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiorgram
X-ray
CT
MRI
Arteriography
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Management Guidelines
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
ASA/ACCF/AHA Guideline Recommendations
Management of Patients With Fibromuscular Dysplasia of the Extracranial Carotid Arteries
Case Studies
Case #1
Fibromuscular dysplasia epidemiology and demographics On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Fibromuscular dysplasia epidemiology and demographics All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Fibromuscular dysplasia epidemiology and demographics
CDC on Fibromuscular dysplasia epidemiology and demographics
Fibromuscular dysplasia epidemiology and demographics in the news
Blogs on Fibromuscular dysplasia epidemiology and demographics
Directions to Hospitals Treating Fibromuscular dysplasia
Risk calculators and risk factors for Fibromuscular dysplasia epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

• The prevalence of FMD in the general population is not known; however, the prevalence of renal artery FMD has been estimated to be as high as 4 per 100 adults.

Patients of all age groups may develop FMD, but women are more commonly affected by FMD than men. The women to men ratio is approximately 9:1.5.

Epidemiology and Demographics

Prevalence

• The prevalence of FMD in the general population is not known; however, the prevalence of renal artery FMD has been estimated to be as high as 4 per 100 adults.
• In one of the largest series of >1000 patients with FMD, 58% had involvement the renal artery, 32% involved the extracranial cerebrovascular arteries and 10% involved other arterial territories such as the visceral arteries or external iliac arteries.

• Approximately 70% of patients have multiple arteries involvement.

• Among patients with renovascular hypertension, FMD accounts for 35 to 50 percent of cases in children and 5 to 10 percent of cases in adults under the age of 60 years.

• Extracranial cerebrovascular (eg, carotid and vertebral arteries) involvement is common in patients with established renal FMD. Data from the first 447 patients entered into the United States FMD Registry reveal that approximately 65 percent have extracranial cerebrovascular disease When cerebrovascular disease is present, there is often bilateral carotid involvement, coexisting vertebral artery disease, and, less commonly, disease in the external carotid, middle cerebral, anterior cerebral, basilar, and anterior communicating arteries. FMD may also be associated with intracranial aneurysms.

Age

• Patients of all age groups may develop FMD.
• The mean age at diagnosis of the first 447 patients enrolled in the U.S. Registry for FMD was 51.9 ± 13.1 years (range of 5 to 86 years),

Gender

• Women are more commonly affected by FMD than men. The women to men ratio is approximately 9:1.5.
• In the US Registry, 91%of registrants were female.