Paroxysmal nocturnal hemoglobinuria screening
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Paroxysmal nocturnal hemoglobinuria Microchapters |
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Differentiating Paroxysmal nocturnal hemoglobinuria from other Diseases |
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Diagnosis |
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Treatment |
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Paroxysmal nocturnal hemoglobinuria screening On the Web |
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American Roentgen Ray Society Images of Paroxysmal nocturnal hemoglobinuria screening |
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Directions to Hospitals Treating Paroxysmal nocturnal hemoglobinuria |
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Risk calculators and risk factors for Paroxysmal nocturnal hemoglobinuria screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Screening
- According to the American society of hematology, screening for paroxysmal nocturnal hemolglobinuria is recommended among patients with:[1]
- Hemoglobinuria
- Cytopenia
- Suspected Myelodysplasia
- Negative direct coombs test intravascular hemolytic anemia
- Refractory anemia
- Aplastic anemia with no apparent sign of intravascular hemolysis
- Unexplained thrombosis especially in unusual sites as:
- Budd-Chiari syndrome
- Other intra-abdominal sites (eg, mesenteric or portal veins)
- Cerebral veins
- Dermal veins
References
- ↑ Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R; et al. (2005). "Diagnosis and management of paroxysmal nocturnal hemoglobinuria". Blood. 106 (12): 3699–709. doi:10.1182/blood-2005-04-1717. PMC 1895106. PMID 16051736.