Hairy cell leukemia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
A positive history of splenomegaly or cytopenias is suggestive of hairy cell leukemia. The most common symptoms of hairy cell leukemia include weakness, fatigue, gingival bleeding, epistaxis and menorrhagia.
History and Symptoms
History
- When evaluating a patient for hairy cell leukemia, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough medication review. Other specific areas of focus when obtaining the history are outlined below:[1]
- Review occupational history related to sawdust exposure
- Review any exposure to radiations
- Review any exposure to herbicides or diesel
Common Symptoms
- Common symptoms of hairy cell leukemia include:
- Fever
- Night sweats
- Fatigue
- Easy bruising or bleeding
- Generalized weakness
- Weight loss
- Recurrent infections
- Early satiety
Less Common Symptoms
Less common symptoms of hairy cell leukemia include
References
- ↑ "How I diagnose and manage individuals at risk for inherited myeloid malignancies". Blood. 128 (14): 1800–1813. 2016. doi:10.1182/blood-2016-05-670240. ISSN 0006-4971.