Multiple sclerosis surgery

	Multiple sclerosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Multiple sclerosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography or Ultrasound
CT Scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Alternative Therapies
Primary Prevention
Secondary Prevention
Tertiary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Multiple sclerosis surgery On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Multiple sclerosis surgery All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Multiple sclerosis surgery
CDC on Multiple sclerosis surgery
Multiple sclerosis surgery in the news
Blogs on Multiple sclerosis surgery
Directions to Hospitals Treating Multiple sclerosis
Risk calculators and risk factors for Multiple sclerosis surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Irfan Dotani

Overview

Surgery can be helpful in managing refractory trigeminal neuralgia, tremors, and ataxia.

Indications

Surgery is not the first-line treatment option for patients with multiple sclerosis, but can be helpful in managing refractory symptoms including:

Trigeminal neuralgia^[1]
Tremor^[2]
Ataxia^[2]

Surgery

Trigeminal neuralgia

If we fail to treat trigeminal neuralgia with medication, surgery can be an option. In order to reduce pain transmission to the brain, we can apply more damage to the nerve and reduce this transmission.^[1]

Tremor and Ataxia

Using surgery for treatment of tremor and ataxia includes thalamotomy and implantation of a thalamic stimulator. Evidence shows that thalamotomy is more effective, but because of more serious side effects, brain stimulation is more preferable.^[2]

References

↑ ^1.0 ^1.1 Kondziolka D, Lunsford LD, Bissonette DJ (1994). "Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia". The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 21 (2): 137–40. PMID 8087740.
↑ ^2.0 ^2.1 ^2.2 Bittar RG, Hyam J, Nandi D, Wang S, Liu X, Joint C, Bain PG, Gregory R, Stein J, Aziz TZ (2005). "Thalamotomy versus thalamic stimulation for multiple sclerosis tremor". Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 12 (6): 638–42. doi:10.1016/j.jocn.2004.09.008. PMID 16098758.

Template:WH Template:WS

[:0-1] 1.0 ^1.1 Kondziolka D, Lunsford LD, Bissonette DJ (1994). "Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia". The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 21 (2): 137–40. PMID 8087740.

[:1-2] 2.0 ^2.1 ^2.2 Bittar RG, Hyam J, Nandi D, Wang S, Liu X, Joint C, Bain PG, Gregory R, Stein J, Aziz TZ (2005). "Thalamotomy versus thalamic stimulation for multiple sclerosis tremor". Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 12 (6): 638–42. doi:10.1016/j.jocn.2004.09.008. PMID 16098758.

[1]

[2]