Endometrial cancer medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The optimal therapy for endometrial cancer depends on the stage at diagnosis. A combination of chemotherapy and radiation therapy is indicated in stages IIIB- IV.
Medical Therapy
- The optimal therapy for endometrial cancer depends on the stage at diagnosis. A combination of chemotherapy and radiation therapy is indicated in stages IIIB- IV.
- Chemotherapy is not the first-line treatment option for patients with stage I-III endometrial cancer. Surgery is the mainstay of treatment.
- Chemotherapy without prior surgery is usually reserved for patients with stage IV endometrial cancer or patients that are not surgical candidates.
- Typically a platinum based combination regimen or triple druge therapy is used:
- Carboplatin + paclitaxel
- Cisplatin + doxorubicin + paclitaxel
- Endocrine therapy is also used with favorable results in patients with:
- Endometroid endmetrial cancer
- Express estrogen and progesterone receptors
- Asymptomatic disease
- Typically a platinum based combination regimen or triple druge therapy is used: