Hypopharyngeal cancer secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Faizan Sheraz, M.D. [3]

Overview

Secondary prevention measures of hypopharyngeal cancer include routine physical examination and imaging at scheduled intervals after treatment. Dental and thyroid screenings for cancers are recommended among the patients who had received radiation therapy to the oral cavity and cervical regions.

Patients treated for hypopharyngeal carcinoma should follow-up for a secondary prevention. Follow-up measures are shown in the table below:^[1]


Follow up	Description

Physical exam	Every 1-3 months during the 1st year after treatment Every 2-6 months during the 2nd year after treatment Every 4-8 months between the 3rd and 5th years after treatment Annually thereafter
Nasendoscopy	Immediately following radiation therapy
CT Scan/MRI	Imaging studies are performed at routine intervals as follows: Baseline scanning is performed at 3-6 months after treatment, further scans are scheduled based on finding of physical exam and symptoms experienced by the patient Scanning for asymptomatic patients is not recommended
Thyroid hormone testing	Thyroid stimulating hormone testing every 12 months if the neck was exposed to radiation
Dental screening	Only recommended if oral cavity was exposed to radiation

↑ Pfister DG, Ang KK, Brizel DM, Burtness BA, Busse PM, Caudell JJ; et al. (2013). "Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines". J Natl Compr Canc Netw. 11 (8): 917–23. PMID 23946171.