Rhabdomyosarcoma other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
No additional tests are recommended for the diagnosis of rhabdomyosarcoma.
Other Diagnostic Tests
Biopsy
- Tissue biopsy considered as most commonly diagnosis in rhabdomyosarcoma.[1]
- There are several ways of taking biopsies which depends on following criteria:[2][3]
- Patients's age
- Primary site of tumor
- Open surgical biopsy is considered as a recommended method to obtaining tissues and proper diagnosis.[4]
- Needle biopsies are considered as less invasive way of taking biopsies.
- Core-needle biopsy
- Fine- needle biopsy
Lumbar puncture
- Lumbar puncture is considered as unnecessary procedure in rhabdomyosarcoma diagnosis.[5]
- Lumbar puncture is usually done in parameningeal rhabdomyosarcoma.
- Also may be considered as a diagnostic study in rhabdomyosarcomas with meningeal involvement.
Bone marrow aspiration and biopsy
- Bone marrow aspiration is usually performed for evaluation of bone marrow involvement due to metastases.
- The samples are taken from pelvic bones.
- It is considered as low yield diagnostic study.
References
- ↑ Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J; et al. (2009). "Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood". Pediatr Blood Cancer. 53 (3): 356–60. doi:10.1002/pbc.22059. PMID 19418540.
- ↑ Nunez AL, Elgin JN, Fatima H (2014). "Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature". Diagn Cytopathol. 42 (12): 1069–74. doi:10.1002/dc.23084. PMID 24599626.
- ↑ Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/
- ↑ PDQ Pediatric Treatment Editorial Board. Childhood Rhabdomyosarcoma Treatment (PDQ®): Patient Version. 2019 Jan 30. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK65839/
- ↑ Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO; et al. (2013). "Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee". J Clin Oncol. 31 (26): 3226–32. doi:10.1200/JCO.2012.44.6476. PMC 3757291. PMID 23940218.