Duchenne muscular dystrophy medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Pharmacologic medical therapies for Duchenne muscular dystrophy include glucocorticoids and disease-modifying treatment.
Medical Therapy
- Pharmacologic medical therapies for Duchenne muscular dystrophy include glucocorticoids and disease-modifying treatment.
Duchenne muscular dystrophy
- 1 Glucocorticoids
- Preferred regimen : Prednisone 0.75 mg/kg PO per day
- 2 Disease-modifying treatment
- Preferred regimen (1): Eteplirsen 30 mg/kg IV per week (infusion over 35 to 60 minutes)
- Preferred regimen (2): Ataluren 40 mg/kg PO per day q8h (10 mg/kg in the morning, 10 mg/kg at midday, and 20 mg/kg in the evening, for a total daily dose of 40 mg/kg.)