Radiation proctitis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
- Symptoms such as diarrhea and painful defectation may be treated with oral opioids and stool softeners, respectively.
- Several other methods are under development as of 2005 to lessen the effects of radiation proctitis. These include sucralfate, hyperbaric oxygen therapy, corticosteroids, metronidazole, and argon plasma coagulation.[2][3][4][5]
References
- ↑ Tabaja L, Sidani SM (2018). "Management of Radiation Proctitis". Dig Dis Sci. 63 (9): 2180–2188. doi:10.1007/s10620-018-5163-8. PMID 29948565.
- ↑ Kochhar R, Patel F, Dhar A, Sharma SC, Ayyagari S, Aggarwal R; et al. (1991). "Radiation-induced proctosigmoiditis. Prospective, randomized, double-blind controlled trial of oral sulfasalazine plus rectal steroids versus rectal sucralfate". Dig Dis Sci. 36 (1): 103–7. PMID 1670631.
- ↑ Talley NA, Chen F, King D, Jones M, Talley NJ (1997). "Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial". Dis Colon Rectum. 40 (9): 1046–50. PMID 9293933.
- ↑ Jensen DM, Machicado GA, Cheng S, Jensen ME, Jutabha R (1997). "A randomized prospective study of endoscopic bipolar electrocoagulation and heater probe treatment of chronic rectal bleeding from radiation telangiectasia". Gastrointest Endosc. 45 (1): 20–5. PMID 9013165.
- ↑ Pinto A, Fidalgo P, Cravo M, Midões J, Chaves P, Rosa J; et al. (1999). "Short chain fatty acids are effective in short-term treatment of chronic radiation proctitis: randomized, double-blind, controlled trial". Dis Colon Rectum. 42 (6): 788–95, discussion 795-6. PMID 10378604.