Central pontine myelinolysis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Epidemiology and Demographics
Incidence and prevalence
- The prevalence of central pontine myelinolysis is approximately 250–500 per 100,000 in the general population.[1]
- Among hospitalized patients in the ICU the incidence of central pontine myelinolysis is approximately 2500 per 100,000 patients.[2][1]
- Among patients undergoing liver transplantation the incidence of central pontine myelinolysis is approximately 10,000 per 100,000 patients.[2][3][1]
Mortality rate
- The case-mortality rate of central pontine myelinolysis is approximately 12%.[1]
Age
- Patients of all age groups may develop central pontine myelinolysis but the incidence of central pontine myelinolysis increases with age.
Race
- There is no racial predilection to central pontine myelinolysis.
Gender
- Central pontine myelinolysis affects men and women equally.[4]
Region
- There is no regional predilection to central pontine myelinolysis.
References
- ↑ 1.0 1.1 1.2 1.3 Rao PB, Azim A, Singh N, Baronia AK, Kumar A, Poddar B (2015). "Osmotic demyelination syndrome in Intensive Care Unit". Indian J Crit Care Med. 19 (3): 166–9. doi:10.4103/0972-5229.152760. PMC 4366916. PMID 25810613.
- ↑ 2.0 2.1 Menger H, Jörg J (1999). "Outcome of central pontine and extrapontine myelinolysis (n = 44)". J Neurol. 246 (8): 700–5. PMID 10460448.
- ↑ Lampl C, Yazdi K (2002). "Central pontine myelinolysis". Eur Neurol. 47 (1): 3–10. doi:10.1159/000047939. PMID 11803185.
- ↑ Bansal LR, Zinkus T (2019). "Osmotic Demyelination Syndrome in Children". Pediatr Neurol. 97: 12–17. doi:10.1016/j.pediatrneurol.2019.03.018. PMID 31128892.